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Human Steroid 17-alpha-hydroxylase 17 20 lyase (aa 25-508)

CYP17 Swiss Prot#

P05093

CYP17 Protein names

Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.99.9) (Cytochrome P450 17A1) (CYPXVII) (Cytochrome P450-C17) (Cytochrome P450c17) (Steroid 17-alpha-monooxygenase)

CYP17 Gene names

CYP17A1 (CYP17) (S17AH)

Organism

Human

CYP17 Entry name

CP17A_HUMAN

CYP17 Codon optimized cDNA(gene) Clone

CYP17 Cat #

RPE0794

Tag

CYP17 contains A 6x histidine tag

CYP17 Formulation

Liquid

CYP17 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYP17 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYP17 Protein

CYP17 Cat #

PE0794

CYP17 Source

recombinant

CYP17 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYP17 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYP17 Activity

N/A

Tag

CYP17 Contains A 6x histidine tag

CYP17 Formulation

Liquid

CYP17 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYP17 family

Cytochrome P450 family

CYP17 Subcellular locations

Membrane.

CYP17 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

CYP17 Sequence

DDBJ

EMBL

GenBank

CYP17 3D structure

ModBase

CYP17 interaction

STRING

CYP17 Proteomic

PRIDE

CYP17 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYP17 Organism specific

CTD

MGI

CYP17 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYP17 Gene expression

Bgee

ArrayExpress

Genevestigator

CYP17 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY