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Human Myocyte-specific enhancer factor 2A (aa 1–507)

MEF2 Swiss Prot#

Q02078

MEF2 Protein names

Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1)

MEF2 Gene names

MEF2A (MEF2)

Organism

Human

MEF2 Entry name

MEF2A_HUMAN

MEF2 Codon optimized cDNA(gene) Clone

MEF2 Cat #

RPE0793

Tag

MEF2 contains A 6x histidine tag

MEF2 Formulation

Liquid

MEF2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MEF2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MEF2 Protein

MEF2 Cat #

PE0793

MEF2 Source

recombinant

MEF2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MEF2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MEF2 Activity

N/A

Tag

MEF2 Contains A 6x histidine tag

MEF2 Formulation

Liquid

MEF2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MEF2 family

MEF2 family

MEF2 Subcellular locations

Nucleus.

MEF2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.

MEF2 Sequence

DDBJ

EMBL

GenBank

MEF2 3D structure

ModBase

MEF2 interaction

STRING

MEF2 Proteomic

PRIDE

MEF2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MEF2 Organism specific

CTD

MGI

MEF2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MEF2 Gene expression

Bgee

ArrayExpress

Genevestigator

MEF2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY