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Human TGF-beta receptor type-1 (aa 205–495)

TGFBR1 Swiss Prot#

P36897

TGFBR1 Protein names

TGF-beta receptor type-1 (EC 2.7.11.30) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TGF-beta type I receptor) (TbetaR-I) (TGFR-1) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5)

TGFBR1 Gene names

TGFBR1

Organism

Human

TGFBR1 Entry name

TGFR1_HUMAN

TGFBR1 Codon optimized cDNA(gene) Clone

TGFBR1 Cat #

RPE0790

Tag

TGFBR1 contains A 6x histidine tag

TGFBR1 Formulation

Liquid

TGFBR1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TGFBR1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TGFBR1 Protein

TGFBR1 Cat #

PE0790

TGFBR1 Source

recombinant

TGFBR1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TGFBR1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TGFBR1 Activity

N/A

Tag

TGFBR1 Contains A 6x histidine tag

TGFBR1 Formulation

Liquid

TGFBR1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TGFBR1 family

Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily

TGFBR1 Subcellular locations

Membrane; Single-pass type I membrane protein.

TGFBR1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

TGFBR1 Sequence

DDBJ

EMBL

GenBank

TGFBR1 3D structure

ModBase

TGFBR1 interaction

STRING

TGFBR1 Proteomic

PRIDE

TGFBR1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TGFBR1 Organism specific

CTD

MGI

TGFBR1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TGFBR1 Gene expression

Bgee

ArrayExpress

Genevestigator

TGFBR1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY