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Human Cytochrome P450 3A4 (aa 30-503)

CYP3A3 Swiss Prot#

P08684

CYP3A3 Protein names

Cytochrome P450 3A4 (Quinine 3-monooxygenase) (EC 1.14.13.67) (CYPIIIA4) (Nifedipine oxidase) (Cytochrome P450 3A3) (CYPIIIA3) (Cytochrome P450 HLp) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Albendazole monooxygenase) (EC 1.14.13.32) (Albendazole sulfoxidase)

CYP3A3 Gene names

CYP3A4 (CYP3A3)

Organism

Human

CYP3A3 Entry name

CP3A4_HUMAN

CYP3A3 Codon optimized cDNA(gene) Clone

CYP3A3 Cat #

RPE0789

Tag

CYP3A3 contains A 6x histidine tag

CYP3A3 Formulation

Liquid

CYP3A3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYP3A3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYP3A3 Protein

CYP3A3 Cat #

PE0789

CYP3A3 Source

recombinant

CYP3A3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYP3A3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYP3A3 Activity

N/A

Tag

CYP3A3 Contains A 6x histidine tag

CYP3A3 Formulation

Liquid

CYP3A3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYP3A3 family

Cytochrome P450 family

CYP3A3 Subcellular locations

Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.

CYP3A3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.

CYP3A3 Sequence

DDBJ

EMBL

GenBank

CYP3A3 3D structure

ModBase

CYP3A3 interaction

STRING

CYP3A3 Proteomic

PRIDE

CYP3A3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYP3A3 Organism specific

CTD

MGI

CYP3A3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYP3A3 Gene expression

Bgee

ArrayExpress

Genevestigator

CYP3A3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY