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Human Potassium voltage-gated channel subfamily H 2 (aa 660–1159)

ERG Swiss Prot#

Q12809

ERG Protein names

Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (ERG-1) (hERG-1) (hERG1) (H-ERG) (Eag homolog)

ERG Gene names

KCNH2 (ERG) (ERG1) (HERG)

Organism

Human

ERG Entry name

KCNH2_HUMAN

ERG Codon optimized cDNA(gene) Clone

ERG Cat #

RPE0784

Tag

ERG contains A 6x histidine tag

ERG Formulation

Liquid

ERG Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ERG Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ERG Protein

ERG Cat #

PE0784

ERG Source

recombinant

ERG Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ERG Purity

>90%, as determined by SDS-PAGE under reducing conditions

ERG Activity

N/A

Tag

ERG Contains A 6x histidine tag

ERG Formulation

Liquid

ERG Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ERG family

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2 sub-subfamily

ERG Subcellular locations

Membrane; Multi-pass membrane protein.

ERG FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.

ERG Sequence

DDBJ

EMBL

GenBank

ERG 3D structure

ModBase

ERG interaction

STRING

ERG Proteomic

PRIDE

ERG Genome annotation

Ensembl

GeneID

KEGG

UCSC

ERG Organism specific

CTD

MGI

ERG Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ERG Gene expression

Bgee

ArrayExpress

Genevestigator

ERG Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY