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Human Mast stem cell growth factor receptor (aa 26–524)

KIT Swiss Prot#

P10721

KIT Protein names

Mast/stem cell growth factor receptor (SCFR) (EC 2.7.10.1) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD antigen CD117)

KIT Gene names

KIT

Organism

Human

KIT Entry name

KIT_HUMAN

KIT Codon optimized cDNA(gene) Clone

KIT Cat #

RPE0781

Tag

KIT contains A 6x histidine tag

KIT Formulation

Liquid

KIT Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

KIT Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant KIT Protein

KIT Cat #

PE0781

KIT Source

recombinant

KIT Applications

Western Blot, SDS-Page or may be used for other applications determined by user

KIT Purity

>90%, as determined by SDS-PAGE under reducing conditions

KIT Activity

N/A

Tag

KIT Contains A 6x histidine tag

KIT Formulation

Liquid

KIT Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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KIT family

Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily

KIT Subcellular locations

Membrane; Single-pass type I membrane protein.

KIT FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K).

KIT Sequence

DDBJ

EMBL

GenBank

KIT 3D structure

ModBase

KIT interaction

STRING

KIT Proteomic

PRIDE

KIT Genome annotation

Ensembl

GeneID

KEGG

UCSC

KIT Organism specific

CTD

MGI

KIT Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KIT Gene expression

Bgee

ArrayExpress

Genevestigator

KIT Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY