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Human Methyl-CpG-binding protein 2 (aa 1–486)

MECP2 Swiss Prot#

P51608

MECP2 Protein names

Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2)

MECP2 Gene names

MECP2

Organism

Human

MECP2 Entry name

MECP2_HUMAN

MECP2 Codon optimized cDNA(gene) Clone

MECP2 Cat #

RPE0766

Tag

MECP2 contains A 6x histidine tag

MECP2 Formulation

Liquid

MECP2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MECP2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MECP2 Protein

MECP2 Cat #

PE0766

MECP2 Source

recombinant

MECP2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MECP2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MECP2 Activity

N/A

Tag

MECP2 Contains A 6x histidine tag

MECP2 Formulation

Liquid

MECP2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MECP2 family

-

MECP2 Subcellular locations

Nucleus.

MECP2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.

MECP2 Sequence

DDBJ

EMBL

GenBank

MECP2 3D structure

ModBase

MECP2 interaction

STRING

MECP2 Proteomic

PRIDE

MECP2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MECP2 Organism specific

CTD

MGI

MECP2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MECP2 Gene expression

Bgee

ArrayExpress

Genevestigator

MECP2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY