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Human Interstitial collagenase (aa 100–269)

CLG Swiss Prot#

P03956

CLG Protein names

Interstitial collagenase (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]

CLG Gene names

MMP1 (CLG)

Organism

Human

CLG Entry name

MMP1_HUMAN

CLG Codon optimized cDNA(gene) Clone

CLG Cat #

RPE0751

Tag

CLG contains A 6x histidine tag

CLG Formulation

Liquid

CLG Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CLG Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CLG Protein

CLG Cat #

PE0751

CLG Source

recombinant

CLG Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CLG Purity

>90%, as determined by SDS-PAGE under reducing conditions

CLG Activity

N/A

Tag

CLG Contains A 6x histidine tag

CLG Formulation

Liquid

CLG Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CLG family

Peptidase M10A family

CLG Subcellular locations

Secreted > extracellular space > extracellular matrix.

CLG FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.

CLG Sequence

DDBJ

EMBL

GenBank

CLG 3D structure

ModBase

CLG interaction

STRING

CLG Proteomic

PRIDE

CLG Genome annotation

Ensembl

GeneID

KEGG

UCSC

CLG Organism specific

CTD

MGI

CLG Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CLG Gene expression

Bgee

ArrayExpress

Genevestigator

CLG Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY