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Human Peroxisome proliferator-activated receptor alpha (aa 1–468)

NR1C1 Swiss Prot#

Q07869

NR1C1 Protein names

Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)

NR1C1 Gene names

PPARA (NR1C1) (PPAR)

Organism

Human

NR1C1 Entry name

PPARA_HUMAN

NR1C1 Codon optimized cDNA(gene) Clone

NR1C1 Cat #

RPE0750

Tag

NR1C1 contains A 6x histidine tag

NR1C1 Formulation

Liquid

NR1C1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NR1C1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NR1C1 Protein

NR1C1 Cat #

PE0750

NR1C1 Source

recombinant

NR1C1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NR1C1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NR1C1 Activity

N/A

Tag

NR1C1 Contains A 6x histidine tag

NR1C1 Formulation

Liquid

NR1C1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NR1C1 family

Nuclear hormone receptor family, NR1 subfamily

NR1C1 Subcellular locations

Nucleus.

NR1C1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

NR1C1 Sequence

DDBJ

EMBL

GenBank

NR1C1 3D structure

ModBase

NR1C1 interaction

STRING

NR1C1 Proteomic

PRIDE

NR1C1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NR1C1 Organism specific

CTD

MGI

NR1C1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NR1C1 Gene expression

Bgee

ArrayExpress

Genevestigator

NR1C1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY