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Human Coagulation factor VII (aa 61–212)
F7 Swiss Prot#
P08709
F7 Protein names
Coagulation factor VII (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain]
F7 Gene names
F7
Organism
Human
F7 Entry name
FA7_HUMAN
F7 Codon optimized cDNA(gene) Clone
F7 Cat #
RPE0746
Tag
F7 contains A 6x histidine tag
F7 Formulation
Liquid
F7 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
F7 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant F7 Protein
F7 Cat #
PE0746
F7 Source
recombinant
F7 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
F7 Purity
>90%, as determined by SDS-PAGE under reducing conditions
F7 Activity
N/A
Tag
F7 Contains A 6x histidine tag
F7 Formulation
Liquid
F7 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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F7 family
Peptidase S1 family
F7 Subcellular locations
Secreted.
F7 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
F7 Sequence
DDBJ EMBL GenBank
F7 3D structure
ModBase
F7 interaction
STRING
F7 Proteomic
PRIDE
F7 Genome annotation
Ensembl GeneID KEGG UCSC
F7 Organism specific
CTD MGI
F7 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
F7 Gene expression
Bgee ArrayExpress Genevestigator
F7 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY