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Human Pyruvate carboxylase (aa 36–486)
PC Swiss Prot#
P11498
PC Protein names
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
PC Gene names
PC
Organism
Human
PC Entry name
PYC_HUMAN
PC Codon optimized cDNA(gene) Clone
PC Cat #
RPE0730
Tag
PC contains A 6x histidine tag
PC Formulation
Liquid
PC Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
PC Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant PC Protein
PC Cat #
PE0730
PC Source
recombinant
PC Applications
Western Blot, SDS-Page or may be used for other applications determined by user
PC Purity
>90%, as determined by SDS-PAGE under reducing conditions
PC Activity
N/A
Tag
PC Contains A 6x histidine tag
PC Formulation
Liquid
PC Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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PC family
-
PC Subcellular locations
Mitochondrion matrix.
PC FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
PC Sequence
DDBJ EMBL GenBank
PC 3D structure
ModBase
PC interaction
STRING
PC Proteomic
PRIDE
PC Genome annotation
Ensembl GeneID KEGG UCSC
PC Organism specific
CTD MGI
PC Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PC Gene expression
Bgee ArrayExpress Genevestigator
PC Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY