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Human Vitamin D3 receptor (aa 1–427)

NR1I1 Swiss Prot#

P11473

NR1I1 Protein names

Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)

NR1I1 Gene names

VDR (NR1I1)

Organism

Human

NR1I1 Entry name

VDR_HUMAN

NR1I1 Codon optimized cDNA(gene) Clone

NR1I1 Cat #

RPE0706

Tag

NR1I1 contains A 6x histidine tag

NR1I1 Formulation

Liquid

NR1I1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NR1I1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NR1I1 Protein

NR1I1 Cat #

PE0706

NR1I1 Source

recombinant

NR1I1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NR1I1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NR1I1 Activity

N/A

Tag

NR1I1 Contains A 6x histidine tag

NR1I1 Formulation

Liquid

NR1I1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NR1I1 family

Nuclear hormone receptor family, NR1 subfamily

NR1I1 Subcellular locations

Nucleus.

NR1I1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

NR1I1 Sequence

DDBJ

EMBL

GenBank

NR1I1 3D structure

ModBase

NR1I1 interaction

STRING

NR1I1 Proteomic

PRIDE

NR1I1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NR1I1 Organism specific

CTD

MGI

NR1I1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NR1I1 Gene expression

Bgee

ArrayExpress

Genevestigator

NR1I1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY