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Human BDNF NT-3 growth factors receptor (aa 32–430)

TRKB Swiss Prot#

Q16620

TRKB Protein names

BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B)

TRKB Gene names

NTRK2 (TRKB)

Organism

Human

TRKB Entry name

NTRK2_HUMAN

TRKB Codon optimized cDNA(gene) Clone

TRKB Cat #

RPE0672

Tag

TRKB contains A 6x histidine tag

TRKB Formulation

Liquid

TRKB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TRKB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TRKB Protein

TRKB Cat #

PE0672

TRKB Source

recombinant

TRKB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TRKB Purity

>90%, as determined by SDS-PAGE under reducing conditions

TRKB Activity

N/A

Tag

TRKB Contains A 6x histidine tag

TRKB Formulation

Liquid

TRKB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TRKB family

Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily

TRKB Subcellular locations

Membrane; Single-pass type I membrane protein.

TRKB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

TRKB Sequence

DDBJ

EMBL

GenBank

TRKB 3D structure

ModBase

TRKB interaction

STRING

TRKB Proteomic

PRIDE

TRKB Genome annotation

Ensembl

GeneID

KEGG

UCSC

TRKB Organism specific

CTD

MGI

TRKB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TRKB Gene expression

Bgee

ArrayExpress

Genevestigator

TRKB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY