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| Human Lysosomal acid lipase cholesteryl ester hydrolase (aa 22–399) |
| LIPA Swiss Prot# | | P38571 |
| LIPA Protein names | | Lysosomal acid lipase/cholesteryl ester hydrolase (LAL) (Acid cholesteryl ester hydrolase) (EC 3.1.1.13) (Sterol esterase) (Lipase A) (Cholesteryl esterase) |
| LIPA Gene names | | LIPA |
| Organism | | Human |
| LIPA Entry name | | LICH_HUMAN |
| LIPA Codon optimized cDNA(gene) Clone |
| LIPA Cat # | | RPE0671 |
| Tag | | LIPA contains A 6x histidine tag |
| LIPA Formulation | | Liquid |
| LIPA Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| LIPA Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant LIPA Protein |
| LIPA Cat # | | PE0671 |
| LIPA Source | | recombinant |
| LIPA Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| LIPA Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| LIPA Activity | | N/A |
| Tag | | LIPA Contains A 6x histidine tag |
| LIPA Formulation | | Liquid |
| LIPA Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant LIPA Products | | For pricing and availability Click Here >>> |
| LIPA family | | AB hydrolase superfamily, Lipase family |
| LIPA Subcellular locations | | Lysosome. |
| LIPA FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. |
| LIPA Sequence | | DDBJ | EMBL | GenBank |
| LIPA 3D structure | | ModBase |
| LIPA interaction | | STRING |
| LIPA Proteomic | | PRIDE |
| LIPA Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| LIPA Organism specific | | CTD | MGI |
| LIPA Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| LIPA Gene expression | | Bgee | ArrayExpress | Genevestigator |
| LIPA Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |