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Human High affinity interleukin-8 receptor B (aa 1–360)

CXCR2 Swiss Prot#

P25025

CXCR2 Protein names

High affinity interleukin-8 receptor B (IL-8R B) (CXCR-2) (GRO/MGSA receptor) (IL-8 receptor type 2) (CDw128b) (CD antigen CD182)

CXCR2 Gene names

IL8RB (CXCR2)

Organism

Human

CXCR2 Entry name

CXCR2_HUMAN

CXCR2 Codon optimized cDNA(gene) Clone

CXCR2 Cat #

RPE0632

Tag

CXCR2 contains A 6x histidine tag

CXCR2 Formulation

Liquid

CXCR2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CXCR2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CXCR2 Protein

CXCR2 Cat #

PE0632

CXCR2 Source

recombinant

CXCR2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CXCR2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CXCR2 Activity

N/A

Tag

CXCR2 Contains A 6x histidine tag

CXCR2 Formulation

Liquid

CXCR2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CXCR2 family

G-protein coupled receptor 1 family

CXCR2 Subcellular locations

Cell membrane; Multi-pass membrane protein.

CXCR2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

CXCR2 Sequence

DDBJ

EMBL

GenBank

CXCR2 3D structure

ModBase

CXCR2 interaction

STRING

CXCR2 Proteomic

PRIDE

CXCR2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CXCR2 Organism specific

CTD

MGI

CXCR2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CXCR2 Gene expression

Bgee

ArrayExpress

Genevestigator

CXCR2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY