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Human Serum paraoxonase arylesterase 1 (aa 2–355)

PON Swiss Prot#

P27169

PON Protein names

Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.8.1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45)

PON Gene names

PON1 (PON)

Organism

Human

PON Entry name

PON1_HUMAN

PON Codon optimized cDNA(gene) Clone

PON Cat #

RPE0628

Tag

PON contains A 6x histidine tag

PON Formulation

Liquid

PON Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PON Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PON Protein

PON Cat #

PE0628

PON Source

recombinant

PON Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PON Purity

>90%, as determined by SDS-PAGE under reducing conditions

PON Activity

N/A

Tag

PON Contains A 6x histidine tag

PON Formulation

Liquid

PON Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PON family

Paraoxonase family

PON Subcellular locations

Secreted > extracellular space.

PON FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

PON Sequence

DDBJ

EMBL

GenBank

PON 3D structure

ModBase

PON interaction

STRING

PON Proteomic

PRIDE

PON Genome annotation

Ensembl

GeneID

KEGG

UCSC

PON Organism specific

CTD

MGI

PON Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PON Gene expression

Bgee

ArrayExpress

Genevestigator

PON Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY