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Human Copper-transporting ATPase 1 (aa 1012–1356)

MC1 Swiss Prot#

Q04656

MC1 Protein names

Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein)

MC1 Gene names

ATP7A (MC1) (MNK)

Organism

Human

MC1 Entry name

ATP7A_HUMAN

MC1 Codon optimized cDNA(gene) Clone

MC1 Cat #

RPE0617

Tag

MC1 contains A 6x histidine tag

MC1 Formulation

Liquid

MC1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MC1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MC1 Protein

MC1 Cat #

PE0617

MC1 Source

recombinant

MC1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MC1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MC1 Activity

N/A

Tag

MC1 Contains A 6x histidine tag

MC1 Formulation

Liquid

MC1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MC1 family

Cation transport ATPase (P-type) (TC 3.A.3) family, Type IB subfamily

MC1 Subcellular locations

Golgi apparatus > trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm > cytosol. Endoplasmic reticulum.

MC1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

MC1 Sequence

DDBJ

EMBL

GenBank

MC1 3D structure

ModBase

MC1 interaction

STRING

MC1 Proteomic

PRIDE

MC1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MC1 Organism specific

CTD

MGI

MC1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MC1 Gene expression

Bgee

ArrayExpress

Genevestigator

MC1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY