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Human N-glycosylase DNA lyase (aa 1–345)

MMH Swiss Prot#

O15527

MMH Protein names

N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)]

MMH Gene names

OGG1 (MMH) (MUTM) (OGH1)

Organism

Human

MMH Entry name

OGG1_HUMAN

MMH Codon optimized cDNA(gene) Clone

MMH Cat #

RPE0615

Tag

MMH contains A 6x histidine tag

MMH Formulation

Liquid

MMH Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MMH Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MMH Protein

MMH Cat #

PE0615

MMH Source

recombinant

MMH Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MMH Purity

>90%, as determined by SDS-PAGE under reducing conditions

MMH Activity

N/A

Tag

MMH Contains A 6x histidine tag

MMH Formulation

Liquid

MMH Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MMH family

Type-1 OGG1 family

MMH Subcellular locations

Nucleus > nucleoplasm. Nucleus speckle. Nucleus matrix. Nucleus. Mitochondrion.

MMH FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

MMH Sequence

DDBJ

EMBL

GenBank

MMH 3D structure

ModBase

MMH interaction

STRING

MMH Proteomic

PRIDE

MMH Genome annotation

Ensembl

GeneID

KEGG

UCSC

MMH Organism specific

CTD

MGI

MMH Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MMH Gene expression

Bgee

ArrayExpress

Genevestigator

MMH Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY