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Human Alcohol dehydrogenase (aa 2–325)

ALDR1 Swiss Prot#

P14550

ALDR1 Protein names

Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1)

ALDR1 Gene names

AKR1A1 (ALDR1) (ALR)

Organism

Human

ALDR1 Entry name

AK1A1_HUMAN

ALDR1 Codon optimized cDNA(gene) Clone

ALDR1 Cat #

RPE0594

Tag

ALDR1 contains A 6x histidine tag

ALDR1 Formulation

Liquid

ALDR1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ALDR1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ALDR1 Protein

ALDR1 Cat #

PE0594

ALDR1 Source

recombinant

ALDR1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ALDR1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ALDR1 Activity

N/A

Tag

ALDR1 Contains A 6x histidine tag

ALDR1 Formulation

Liquid

ALDR1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ALDR1 family

Aldo/keto reductase family

ALDR1 Subcellular locations

-

ALDR1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

ALDR1 Sequence

DDBJ

EMBL

GenBank

ALDR1 3D structure

ModBase

ALDR1 interaction

STRING

ALDR1 Proteomic

PRIDE

ALDR1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ALDR1 Organism specific

CTD

MGI

ALDR1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ALDR1 Gene expression

Bgee

ArrayExpress

Genevestigator

ALDR1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY