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Human Angiotensin-converting enzyme (aa 30-350)

DCP Swiss Prot#

P12821

DCP Protein names

Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (EC 3.2.1.-) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]

DCP Gene names

ACE (DCP) (DCP1)

Organism

Human

DCP Entry name

ACE_HUMAN

DCP Codon optimized cDNA(gene) Clone

DCP Cat #

RPE0591

Tag

DCP contains A 6x histidine tag

DCP Formulation

Liquid

DCP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DCP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DCP Protein

DCP Cat #

PE0591

DCP Source

recombinant

DCP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DCP Purity

>90%, as determined by SDS-PAGE under reducing conditions

DCP Activity

N/A

Tag

DCP Contains A 6x histidine tag

DCP Formulation

Liquid

DCP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DCP family

Peptidase M2 family

DCP Subcellular locations

Secreted. Cell membrane; Single-pass type I membrane protein.

DCP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

DCP Sequence

DDBJ

EMBL

GenBank

DCP 3D structure

ModBase

DCP interaction

STRING

DCP Proteomic

PRIDE

DCP Genome annotation

Ensembl

GeneID

KEGG

UCSC

DCP Organism specific

CTD

MGI

DCP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DCP Gene expression

Bgee

ArrayExpress

Genevestigator

DCP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY