All rights reserved

Bio-Magnetic Purification ......   A Powerful Tool for Life Science Research Affinity Magnetic Beads >>> Amine >>                 Aldehyde >>                  Carboxy >>    CDI >>                      DVS >>                          DADPA  >>     Epoxy  >>                 Hydrazide >>                 Hyrdoxy >>     Iodoacetyl >>           NHS >>                         Sulghydry >> Tosyl >>                   Thiol >>                         Silica >> EDTA >>                   IDA >>                      Streptavidin  >> Monomer Avidin >>          Reversed-Phase Magnetic Beads >>> C4 >>                          C8 >>                       C18 >>   Cyanopropyl >>          Phenyl >>                 Dipheny >> Ion Exchange Magnetic Beads >>> DEAE >>                   PSA >>                  SAX >> WCX >>                    SCX >>           Hydroxyapatite  >> Antibody Purification & IP >>> Protein A >>           Protein G >>        Protein A/G >> Protein L >> Recombinant Protein Purification >>> Ni+ Charged Beads >>    Co + Charged Beads >> GST >> DNA & RNA Purification >>> Plant/Animal >>         Bacteria >>             Blood >> Saliva >>                   Stool >>                  Food >> mRNA >>                    PCR >>                   Soil >> Endotoxin Removal Magnetic Beads >>>   Abundant Protein Removal >>> HSA  Removal >>                                    IgG  Removal >> Cell Isolation >>> Bacteria >>                                              Viurs >> More Application >>

Home BioMagnetic Beads Recombinant Protein & Codon Optimized cDNA Service Order Contact Us New Products

For cDNA or Recombinant Protein Search ( Input   Gene name, or Protein Name, or Swiss -prot Accession Number Bioclone Distributor >>>

Email: info@bioclone.us ;  order@bioclone.us

More Than 20,000   Recombinant Protein & cDNA(gene) Virus Antigen  >>> Bacterial Antigen >>> Parasite Antigen  >>> Cell Surface CD Marker >> Cytokines >>> Kinase  >>> Transduction >>> Transcription Factor >>> Common Disease-related Proteins >>> Phosphatase >>> Cancer >>> Drug  metabolism >>> Neuroscience >>> G protein coupled receptors   >>> Stem cell >> Kinase >>> Disease >.>> Toxin & Allergen >>> Cytoskeleton >>

Human Inhibitor nuclear factor kappa-B kinase (aa 15–302)

IKKA Swiss Prot#

O15111

IKKA Protein names

Inhibitor of nuclear factor kappa-B kinase subunit alpha (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (EC 2.7.11.10) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)

IKKA Gene names

CHUK (IKKA) (TCF16)

Organism

Human

IKKA Entry name

IKKA_HUMAN

IKKA Codon optimized cDNA(gene) Clone

IKKA Cat #

RPE0563

Tag

IKKA contains A 6x histidine tag

IKKA Formulation

Liquid

IKKA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IKKA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IKKA Protein

IKKA Cat #

PE0563

IKKA Source

recombinant

IKKA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IKKA Purity

>90%, as determined by SDS-PAGE under reducing conditions

IKKA Activity

N/A

Tag

IKKA Contains A 6x histidine tag

IKKA Formulation

Liquid

IKKA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Place Order for Recombinant IKKA Products

For pricing and availability Click Here >>>

IKKA family

Protein kinase superfamily, Ser/Thr protein kinase family, I-kappa-B kinase subfamily

IKKA Subcellular locations

Cytoplasm. Nucleus.

IKKA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.

IKKA Sequence

DDBJ

EMBL

GenBank

IKKA 3D structure

ModBase

IKKA interaction

STRING

IKKA Proteomic

PRIDE

IKKA Genome annotation

Ensembl

GeneID

KEGG

UCSC

IKKA Organism specific

CTD

MGI

IKKA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IKKA Gene expression

Bgee

ArrayExpress

Genevestigator

IKKA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY