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Human Mitogen-activated protein kinase 1 (aa 1243–1508)

MAPKKK1 Swiss Prot#

Q13233

MAPKKK1 Protein names

Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1)

MAPKKK1 Gene names

MAP3K1 (MAPKKK1) (MEKK) (MEKK1)

Organism

Human

MAPKKK1 Entry name

M3K1_HUMAN

MAPKKK1 Codon optimized cDNA(gene) Clone

MAPKKK1 Cat #

RPE0538

Tag

MAPKKK1 contains A 6x histidine tag

MAPKKK1 Formulation

Liquid

MAPKKK1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MAPKKK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MAPKKK1 Protein

MAPKKK1 Cat #

PE0538

MAPKKK1 Source

recombinant

MAPKKK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MAPKKK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MAPKKK1 Activity

N/A

Tag

MAPKKK1 Contains A 6x histidine tag

MAPKKK1 Formulation

Liquid

MAPKKK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MAPKKK1 family

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily

MAPKKK1 Subcellular locations

-

MAPKKK1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

MAPKKK1 Sequence

DDBJ

EMBL

GenBank

MAPKKK1 3D structure

ModBase

MAPKKK1 interaction

STRING

MAPKKK1 Proteomic

PRIDE

MAPKKK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MAPKKK1 Organism specific

CTD

MGI

MAPKKK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MAPKKK1 Gene expression

Bgee

ArrayExpress

Genevestigator

MAPKKK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY