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Human RAF proto-oncogene serine threonine-protein (aa 349–609)

RAF Swiss Prot#

P04049

RAF Protein names

RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (C-RAF) (cRaf) (Raf-1)

RAF Gene names

RAF1 (RAF)

Organism

Human

RAF Entry name

RAF1_HUMAN

RAF Codon optimized cDNA(gene) Clone

RAF Cat #

RPE0531

Tag

RAF contains A 6x histidine tag

RAF Formulation

Liquid

RAF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RAF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RAF Protein

RAF Cat #

PE0531

RAF Source

recombinant

RAF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RAF Purity

>90%, as determined by SDS-PAGE under reducing conditions

RAF Activity

N/A

Tag

RAF Contains A 6x histidine tag

RAF Formulation

Liquid

RAF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RAF family

Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily

RAF Subcellular locations

-

RAF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

RAF Sequence

DDBJ

EMBL

GenBank

RAF 3D structure

ModBase

RAF interaction

STRING

RAF Proteomic

PRIDE

RAF Genome annotation

Ensembl

GeneID

KEGG

UCSC

RAF Organism specific

CTD

MGI

RAF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RAF Gene expression

Bgee

ArrayExpress

Genevestigator

RAF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY