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Human Prothrombin (aa 364–622)

F2 Swiss Prot#

P00734

F2 Protein names

Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]

F2 Gene names

F2

Organism

Human

F2 Entry name

THRB_HUMAN

F2 Codon optimized cDNA(gene) Clone

F2 Cat #

RPE0520

Tag

F2 contains A 6x histidine tag

F2 Formulation

Liquid

F2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

F2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant F2 Protein

F2 Cat #

PE0520

F2 Source

recombinant

F2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

F2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

F2 Activity

N/A

Tag

F2 Contains A 6x histidine tag

F2 Formulation

Liquid

F2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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F2 family

Peptidase S1 family

F2 Subcellular locations

Secreted > extracellular space.

F2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

F2 Sequence

DDBJ

EMBL

GenBank

F2 3D structure

ModBase

F2 interaction

STRING

F2 Proteomic

PRIDE

F2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

F2 Organism specific

CTD

MGI

F2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

F2 Gene expression

Bgee

ArrayExpress

Genevestigator

F2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY