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Human T-cell surface glycoprotein CD8 alpha chain (aa 22–182)
MAL Swiss Prot#
P01732
MAL Protein names
T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)
MAL Gene names
CD8A (MAL)
Organism
Human
MAL Entry name
CD8A_HUMAN
MAL Codon optimized cDNA(gene) Clone
MAL Cat #
RPE0494
Tag
MAL contains A 6x histidine tag
MAL Formulation
Liquid
MAL Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
MAL Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant MAL Protein
MAL Cat #
PE0494
MAL Source
recombinant
MAL Applications
Western Blot, SDS-Page or may be used for other applications determined by user
MAL Purity
>90%, as determined by SDS-PAGE under reducing conditions
MAL Activity
N/A
Tag
MAL Contains A 6x histidine tag
MAL Formulation
Liquid
MAL Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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MAL family
-
MAL Subcellular locations
Cell membrane; Single-pass type I membrane protein. Secreted.
MAL FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
MAL Sequence
DDBJ EMBL GenBank
MAL 3D structure
ModBase
MAL interaction
STRING
MAL Proteomic
PRIDE
MAL Genome annotation
Ensembl GeneID KEGG UCSC
MAL Organism specific
CTD MGI
MAL Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MAL Gene expression
Bgee ArrayExpress Genevestigator
MAL Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY