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Human Vascular endothelial growth factor A (aa 27–232)

VEGF Swiss Prot#

P15692

VEGF Protein names

Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF)

VEGF Gene names

VEGFA (VEGF)

Organism

Human

VEGF Entry name

VEGFA_HUMAN

VEGF Codon optimized cDNA(gene) Clone

VEGF Cat #

RPE0491

Tag

VEGF contains A 6x histidine tag

VEGF Formulation

Liquid

VEGF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

VEGF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant VEGF Protein

VEGF Cat #

PE0491

VEGF Source

recombinant

VEGF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

VEGF Purity

>90%, as determined by SDS-PAGE under reducing conditions

VEGF Activity

N/A

Tag

VEGF Contains A 6x histidine tag

VEGF Formulation

Liquid

VEGF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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VEGF family

PDGF/VEGF growth factor family

VEGF Subcellular locations

Secreted.

VEGF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

VEGF Sequence

DDBJ

EMBL

GenBank

VEGF 3D structure

ModBase

VEGF interaction

STRING

VEGF Proteomic

PRIDE

VEGF Genome annotation

Ensembl

GeneID

KEGG

UCSC

VEGF Organism specific

CTD

MGI

VEGF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

VEGF Gene expression

Bgee

ArrayExpress

Genevestigator

VEGF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY