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Human Hypoxanthine-guanine phosphoribosyl transferase (aa 1-218)

HPRT Swiss Prot#

P00492

HPRT Protein names

Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) (HGPRT) (EC 2.4.2.8)

HPRT Gene names

HPRT1 (HPRT)

Organism

Human

HPRT Entry name

HPRT_HUMAN

HPRT Codon optimized cDNA(gene) Clone

HPRT Cat #

RPE0479

Tag

HPRT contains A 6x histidine tag

HPRT Formulation

Liquid

HPRT Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

HPRT Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant HPRT Protein

HPRT Cat #

PE0479

HPRT Source

recombinant

HPRT Applications

Western Blot, SDS-Page or may be used for other applications determined by user

HPRT Purity

>90%, as determined by SDS-PAGE under reducing conditions

HPRT Activity

N/A

Tag

HPRT Contains A 6x histidine tag

HPRT Formulation

Liquid

HPRT Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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HPRT family

Purine/pyrimidine phosphoribosyltransferase family

HPRT Subcellular locations

Cytoplasm.

HPRT FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.

HPRT Sequence

DDBJ

EMBL

GenBank

HPRT 3D structure

ModBase

HPRT interaction

STRING

HPRT Proteomic

PRIDE

HPRT Genome annotation

Ensembl

GeneID

KEGG

UCSC

HPRT Organism specific

CTD

MGI

HPRT Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

HPRT Gene expression

Bgee

ArrayExpress

Genevestigator

HPRT Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY