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Human High mobility group protein B1 (aa 2–215)

HMG1 Swiss Prot#

P09429

HMG1 Protein names

High mobility group protein B1 (High mobility group protein 1) (HMG-1)

HMG1 Gene names

HMGB1 (HMG1)

Organism

Human

HMG1 Entry name

HMGB1_HUMAN

HMG1 Codon optimized cDNA(gene) Clone

HMG1 Cat #

RPE0474

Tag

HMG1 contains A 6x histidine tag

HMG1 Formulation

Liquid

HMG1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

HMG1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant HMG1 Protein

HMG1 Cat #

PE0474

HMG1 Source

recombinant

HMG1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

HMG1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

HMG1 Activity

N/A

Tag

HMG1 Contains A 6x histidine tag

HMG1 Formulation

Liquid

HMG1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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HMG1 family

HMGB family

HMG1 Subcellular locations

Nucleus. Chromosome.

HMG1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).

HMG1 Sequence

DDBJ

EMBL

GenBank

HMG1 3D structure

ModBase

HMG1 interaction

STRING

HMG1 Proteomic

PRIDE

HMG1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

HMG1 Organism specific

CTD

MGI

HMG1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

HMG1 Gene expression

Bgee

ArrayExpress

Genevestigator

HMG1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY