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Human Protein FADD (aa 1–208)

MORT1 Swiss Prot#

Q13158

MORT1 Protein names

Protein FADD (FAS-associated death domain protein) (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity) (Growth-inhibiting gene 3 protein)

MORT1 Gene names

FADD (MORT1) (GIG3)

Organism

Human

MORT1 Entry name

FADD_HUMAN

MORT1 Codon optimized cDNA(gene) Clone

MORT1 Cat #

RPE0468

Tag

MORT1 contains A 6x histidine tag

MORT1 Formulation

Liquid

MORT1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MORT1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MORT1 Protein

MORT1 Cat #

PE0468

MORT1 Source

recombinant

MORT1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MORT1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MORT1 Activity

N/A

Tag

MORT1 Contains A 6x histidine tag

MORT1 Formulation

Liquid

MORT1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MORT1 family

-

MORT1 Subcellular locations

-

MORT1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

MORT1 Sequence

DDBJ

EMBL

GenBank

MORT1 3D structure

ModBase

MORT1 interaction

STRING

MORT1 Proteomic

PRIDE

MORT1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MORT1 Organism specific

CTD

MGI

MORT1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MORT1 Gene expression

Bgee

ArrayExpress

Genevestigator

MORT1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY