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Human Cyclin-dependent kinase inhibitor 1B (aa 1-153)

KIP1 Swiss Prot#

P46527

KIP1 Protein names

Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)

KIP1 Gene names

CDKN1B (KIP1)

Organism

Human

KIP1 Entry name

CDN1B_HUMAN

KIP1 Codon optimized cDNA(gene) Clone

KIP1 Cat #

RPE0459

Tag

KIP1 contains A 6x histidine tag

KIP1 Formulation

Liquid

KIP1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

KIP1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant KIP1 Protein

KIP1 Cat #

PE0459

KIP1 Source

recombinant

KIP1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

KIP1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

KIP1 Activity

N/A

Tag

KIP1 Contains A 6x histidine tag

KIP1 Formulation

Liquid

KIP1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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KIP1 family

CDI family

KIP1 Subcellular locations

Nucleus. Cytoplasm. Endosome.

KIP1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

KIP1 Sequence

DDBJ

EMBL

GenBank

KIP1 3D structure

ModBase

KIP1 interaction

STRING

KIP1 Proteomic

PRIDE

KIP1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

KIP1 Organism specific

CTD

MGI

KIP1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KIP1 Gene expression

Bgee

ArrayExpress

Genevestigator

KIP1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY