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Human Transforming protein RhoA (aa 1–190) |
ARH12 Swiss Prot# | | P61586 |
ARH12 Protein names | | Transforming protein RhoA (H12) |
ARH12 Gene names | | RHOA (ARH12) (ARHA) (RHO12) |
Organism | | Human |
ARH12 Entry name | | RHOA_HUMAN |
ARH12 Codon optimized cDNA(gene) Clone |
ARH12 Cat # | | RPE0454 |
Tag | | ARH12 contains A 6x histidine tag |
ARH12 Formulation | | Liquid |
ARH12 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
ARH12 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
Recombinant ARH12 Protein |
ARH12 Cat # | | PE0454 |
ARH12 Source | | recombinant |
ARH12 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
ARH12 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
ARH12 Activity | | N/A |
Tag | | ARH12 Contains A 6x histidine tag |
ARH12 Formulation | | Liquid |
ARH12 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
Place Order for Recombinant ARH12 Products | | For pricing and availability Click Here >>> |
ARH12 family | | Small GTPase superfamily, Rho family |
ARH12 Subcellular locations | | Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm > cytoskeleton. |
ARH12 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. |
ARH12 Sequence | | DDBJ | EMBL | GenBank |
ARH12 3D structure | | ModBase |
ARH12 interaction | | STRING |
ARH12 Proteomic | | PRIDE |
ARH12 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
ARH12 Organism specific | | CTD | MGI |
ARH12 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| InParanoid | OrthoDB | PhylomeDB | OMA |
ARH12 Gene expression | | Bgee | ArrayExpress | Genevestigator |
ARH12 Family and domain | | InterPro | PROSITE | ProtoNet |
FOR in vitro RESEARCH USE ONLY |