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Human Transforming protein RhoA (aa 1–190)
ARH12 Swiss Prot#
P61586
ARH12 Protein names
Transforming protein RhoA (H12)
ARH12 Gene names
RHOA (ARH12) (ARHA) (RHO12)
Organism
Human
ARH12 Entry name
RHOA_HUMAN
ARH12 Codon optimized cDNA(gene) Clone
ARH12 Cat #
RPE0454
Tag
ARH12 contains A 6x histidine tag
ARH12 Formulation
Liquid
ARH12 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
ARH12 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant ARH12 Protein
ARH12 Cat #
PE0454
ARH12 Source
recombinant
ARH12 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
ARH12 Purity
>90%, as determined by SDS-PAGE under reducing conditions
ARH12 Activity
N/A
Tag
ARH12 Contains A 6x histidine tag
ARH12 Formulation
Liquid
ARH12 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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ARH12 family
Small GTPase superfamily, Rho family
ARH12 Subcellular locations
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm > cytoskeleton.
ARH12 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.
ARH12 Sequence
DDBJ EMBL GenBank
ARH12 3D structure
ModBase
ARH12 interaction
STRING
ARH12 Proteomic
PRIDE
ARH12 Genome annotation
Ensembl GeneID KEGG UCSC
ARH12 Organism specific
CTD MGI
ARH12 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ARH12 Gene expression
Bgee ArrayExpress Genevestigator
ARH12 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY