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Human Mediator RNA polymerase II transcription subunit 28 (aa 1-178)

EG1 Swiss Prot#

Q9H204

EG1 Protein names

Mediator of RNA polymerase II transcription subunit 28 (Mediator complex subunit 28) (Tumor angiogenesis marker EG-1) (Endothelial-derived protein 1) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin)

EG1 Gene names

MED28 (EG1) (FKSG20)

Organism

Human

EG1 Entry name

MED28_HUMAN

EG1 Codon optimized cDNA(gene) Clone

EG1 Cat #

RPE0439

Tag

EG1 contains A 6x histidine tag

EG1 Formulation

Liquid

EG1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EG1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EG1 Protein

EG1 Cat #

PE0439

EG1 Source

recombinant

EG1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EG1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

EG1 Activity

N/A

Tag

EG1 Contains A 6x histidine tag

EG1 Formulation

Liquid

EG1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EG1 family

Mediator complex subunit 28 family

EG1 Subcellular locations

Nucleus. Cytoplasm. Membrane; Peripheral membrane protein.

EG1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.

EG1 Sequence

DDBJ

EMBL

GenBank

EG1 3D structure

ModBase

EG1 interaction

STRING

EG1 Proteomic

PRIDE

EG1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

EG1 Organism specific

CTD

MGI

EG1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EG1 Gene expression

Bgee

ArrayExpress

Genevestigator

EG1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY