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Human Caveolin-1 (aa 2–178)

CAV Swiss Prot#

Q03135

CAV Protein names

Caveolin-1

CAV Gene names

CAV1 (CAV)

Organism

Human

CAV Entry name

CAV1_HUMAN

CAV Codon optimized cDNA(gene) Clone

CAV Cat #

RPE0438

Tag

CAV contains A 6x histidine tag

CAV Formulation

Liquid

CAV Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CAV Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CAV Protein

CAV Cat #

PE0438

CAV Source

recombinant

CAV Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CAV Purity

>90%, as determined by SDS-PAGE under reducing conditions

CAV Activity

N/A

Tag

CAV Contains A 6x histidine tag

CAV Formulation

Liquid

CAV Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CAV family

Caveolin family

CAV Subcellular locations

Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane > caveola; Peripheral membrane protein. Membrane raft.

CAV FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

CAV Sequence

DDBJ

EMBL

GenBank

CAV 3D structure

ModBase

CAV interaction

STRING

CAV Proteomic

PRIDE

CAV Genome annotation

Ensembl

GeneID

KEGG

UCSC

CAV Organism specific

CTD

MGI

CAV Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CAV Gene expression

Bgee

ArrayExpress

Genevestigator

CAV Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY