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Human Bcl2 antagonist cell death (aa 1–168)

BBC6 Swiss Prot#

Q92934

BBC6 Protein names

Bcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-XL/Bcl-2-associated death promoter)

BBC6 Gene names

BAD (BBC6) (BCL2L8)

Organism

Human

BBC6 Entry name

BAD_HUMAN

BBC6 Codon optimized cDNA(gene) Clone

BBC6 Cat #

RPE0430

Tag

BBC6 contains A 6x histidine tag

BBC6 Formulation

Liquid

BBC6 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BBC6 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BBC6 Protein

BBC6 Cat #

PE0430

BBC6 Source

recombinant

BBC6 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BBC6 Purity

>90%, as determined by SDS-PAGE under reducing conditions

BBC6 Activity

N/A

Tag

BBC6 Contains A 6x histidine tag

BBC6 Formulation

Liquid

BBC6 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BBC6 family

Bcl-2 family

BBC6 Subcellular locations

Mitochondrion outer membrane. Cytoplasm.

BBC6 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

BBC6 Sequence

DDBJ

EMBL

GenBank

BBC6 3D structure

ModBase

BBC6 interaction

STRING

BBC6 Proteomic

PRIDE

BBC6 Genome annotation

Ensembl

GeneID

KEGG

UCSC

BBC6 Organism specific

CTD

MGI

BBC6 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BBC6 Gene expression

Bgee

ArrayExpress

Genevestigator

BBC6 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY