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Human PIAS1 (aa 124–288)

DDXBP1 Swiss Prot#

O75925

DDXBP1 Protein names

PIAS1 (DDXBP1)

DDXBP1 Gene names

DDXBP1

Organism

Human

DDXBP1 Entry name

PIAS1_HUMAN

DDXBP1 Codon optimized cDNA(gene) Clone

DDXBP1 Cat #

RPE0429

Tag

DDXBP1 contains A 6x histidine tag

DDXBP1 Formulation

Liquid

DDXBP1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DDXBP1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DDXBP1 Protein

DDXBP1 Cat #

PE0429

DDXBP1 Source

recombinant

DDXBP1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DDXBP1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DDXBP1 Activity

N/A

Tag

DDXBP1 Contains A 6x histidine tag

DDXBP1 Formulation

Liquid

DDXBP1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DDXBP1 family

PIAS family

DDXBP1 Subcellular locations

Nucleus speckle.

DDXBP1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling.

DDXBP1 Sequence

DDBJ

EMBL

GenBank

DDXBP1 3D structure

ModBase

DDXBP1 interaction

STRING

DDXBP1 Proteomic

PRIDE

DDXBP1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DDXBP1 Organism specific

CTD

MGI

DDXBP1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DDXBP1 Gene expression

Bgee

ArrayExpress

Genevestigator

DDXBP1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY