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Human Thioredoxin (aa 2–105)

TRDX Swiss Prot#

P10599

TRDX Protein names

Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP)

TRDX Gene names

TXN (TRDX) (TRX) (TRX1)

Organism

Human

TRDX Entry name

THIO_HUMAN

TRDX Codon optimized cDNA(gene) Clone

TRDX Cat #

RPE0410

Tag

TRDX contains A 6x histidine tag

TRDX Formulation

Liquid

TRDX Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TRDX Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TRDX Protein

TRDX Cat #

PE0410

TRDX Source

recombinant

TRDX Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TRDX Purity

>90%, as determined by SDS-PAGE under reducing conditions

TRDX Activity

N/A

Tag

TRDX Contains A 6x histidine tag

TRDX Formulation

Liquid

TRDX Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TRDX family

Thioredoxin family

TRDX Subcellular locations

Nucleus. Cytoplasm. Secreted.

TRDX FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.; FUNCTION: ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

TRDX Sequence

DDBJ

EMBL

GenBank

TRDX 3D structure

ModBase

TRDX interaction

STRING

TRDX Proteomic

PRIDE

TRDX Genome annotation

Ensembl

GeneID

KEGG

UCSC

TRDX Organism specific

CTD

MGI

TRDX Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TRDX Gene expression

Bgee

ArrayExpress

Genevestigator

TRDX Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY