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Human Cytochrome c (aa 2–105)

CYC Swiss Prot#

P99999

CYC Protein names

Cytochrome c

CYC Gene names

CYCS (CYC)

Organism

Human

CYC Entry name

CYC_HUMAN

CYC Codon optimized cDNA(gene) Clone

CYC Cat #

RPE0409

Tag

CYC contains A 6x histidine tag

CYC Formulation

Liquid

CYC Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYC Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYC Protein

CYC Cat #

PE0409

CYC Source

recombinant

CYC Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYC Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYC Activity

N/A

Tag

CYC Contains A 6x histidine tag

CYC Formulation

Liquid

CYC Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYC family

Cytochrome c family

CYC Subcellular locations

Mitochondrion matrix.

CYC FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; FUNCTION: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

CYC Sequence

DDBJ

EMBL

GenBank

CYC 3D structure

ModBase

CYC interaction

STRING

CYC Proteomic

PRIDE

CYC Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYC Organism specific

CTD

MGI

CYC Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYC Gene expression

Bgee

ArrayExpress

Genevestigator

CYC Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY