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Human Insulin receptor substrate 1 (aa 160–264)

IRS1 Swiss Prot#

P35568

IRS1 Protein names

Insulin receptor substrate 1 (IRS-1)

IRS1 Gene names

IRS1

Organism

Human

IRS1 Entry name

IRS1_HUMAN

IRS1 Codon optimized cDNA(gene) Clone

IRS1 Cat #

RPE0408

Tag

IRS1 contains A 6x histidine tag

IRS1 Formulation

Liquid

IRS1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IRS1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IRS1 Protein

IRS1 Cat #

PE0408

IRS1 Source

recombinant

IRS1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IRS1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

IRS1 Activity

N/A

Tag

IRS1 Contains A 6x histidine tag

IRS1 Formulation

Liquid

IRS1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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IRS1 family

-

IRS1 Subcellular locations

-

IRS1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

IRS1 Sequence

DDBJ

EMBL

GenBank

IRS1 3D structure

ModBase

IRS1 interaction

STRING

IRS1 Proteomic

PRIDE

IRS1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

IRS1 Organism specific

CTD

MGI

IRS1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IRS1 Gene expression

Bgee

ArrayExpress

Genevestigator

IRS1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY