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Human Interleukin-8 (aa 21-90)
CXCL8 Swiss Prot#
P10145
CXCL8 Protein names
Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (T-cell chemotactic factor) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Emoctakin) [Cleaved into: MDNCF-a (IL8/NAP1 form I) (GCP/IL-8 protein IV); Interleukin-8 (IL-8(1-77)) (MDNCF-b) (IL8/NAP1 form II) (GCP/IL-8 protein II) ((Ala-IL-8)77); IL-8(5-77); IL-8(6-77) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (Neutrophil-activating factor) (NAF) (MDNCF-c) (IL8/NAP1 form III) (GCP/IL-8 protein I) ((Ser-IL-8)72); IL-8(7-77) (IL8/NAP1 form IV) (GCP/IL-8 protein V); IL-8(8-77) (IL8/NAP1 form V) (GCP/IL-8 protein VI); IL-8(9-77) (IL8/NAP1 form VI) (GCP/IL-8 protein III)]
CXCL8 Gene names
IL8 (CXCL8)
Organism
Human
CXCL8 Entry name
IL8_HUMAN
CXCL8 Codon optimized cDNA(gene) Clone
CXCL8 Cat #
RPE0405
Tag
CXCL8 contains A 6x histidine tag
CXCL8 Formulation
Liquid
CXCL8 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
CXCL8 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant CXCL8 Protein
CXCL8 Cat #
PE0405
CXCL8 Source
recombinant
CXCL8 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
CXCL8 Purity
>90%, as determined by SDS-PAGE under reducing conditions
CXCL8 Activity
N/A
Tag
CXCL8 Contains A 6x histidine tag
CXCL8 Formulation
Liquid
CXCL8 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CXCL8 family
Intercrine alpha (chemokine CxC) family
CXCL8 Subcellular locations
Secreted.
CXCL8 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
CXCL8 Sequence
DDBJ EMBL GenBank
CXCL8 3D structure
ModBase
CXCL8 interaction
STRING
CXCL8 Proteomic
PRIDE
CXCL8 Genome annotation
Ensembl GeneID KEGG UCSC
CXCL8 Organism specific
CTD MGI
CXCL8 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CXCL8 Gene expression
Bgee ArrayExpress Genevestigator
CXCL8 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY