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Human Fibronectin (aa 627–702)

FN Swiss Prot#

P02751

FN Protein names

Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]

FN Gene names

FN1 (FN)

Organism

Human

FN Entry name

FINC_HUMAN

FN Codon optimized cDNA(gene) Clone

FN Cat #

RPE0402

Tag

FN contains A 6x histidine tag

FN Formulation

Liquid

FN Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FN Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FN Protein

FN Cat #

PE0402

FN Source

recombinant

FN Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FN Purity

>90%, as determined by SDS-PAGE under reducing conditions

FN Activity

N/A

Tag

FN Contains A 6x histidine tag

FN Formulation

Liquid

FN Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FN family

-

FN Subcellular locations

Secreted > extracellular space > extracellular matrix.

FN FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape.; FUNCTION: Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

FN Sequence

DDBJ

EMBL

GenBank

FN 3D structure

ModBase

FN interaction

STRING

FN Proteomic

PRIDE

FN Genome annotation

Ensembl

GeneID

KEGG

UCSC

FN Organism specific

CTD

MGI

FN Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FN Gene expression

Bgee

ArrayExpress

Genevestigator

FN Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY