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Mouse Heparanase (aa 28-535)

Hpa Swiss Prot#

Q6YGZ1

Hpa Protein names

Heparanase (EC 3.2.-.-) (Endo-glucoronidase) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit]

Hpa Gene names

Hpse (Hpa)

Organism

Mouse

Hpa Entry name

HPSE_MOUSE

Hpa Codon optimized cDNA(gene) Clone

Hpa Cat #

RPE0382

Tag

Hpa contains A 6x histidine tag

Hpa Formulation

Liquid

Hpa Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Hpa Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Hpa Protein

Hpa Cat #

PE0382

Hpa Source

recombinant

Hpa Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Hpa Purity

>90%, as determined by SDS-PAGE under reducing conditions

Hpa Activity

N/A

Tag

Hpa Contains A 6x histidine tag

Hpa Formulation

Liquid

Hpa Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Hpa family

Glycosyl hydrolase 79 family

Hpa Subcellular locations

Lysosome membrane; Peripheral membrane protein. Secreted.

Hpa FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Contributes to metastasis and angiogenesis (By similarity).

Hpa Sequence

DDBJ

EMBL

GenBank

Hpa 3D structure

ModBase

Hpa interaction

STRING

Hpa Proteomic

PRIDE

Hpa Genome annotation

Ensembl

GeneID

KEGG

UCSC

Hpa Organism specific

CTD

MGI

Hpa Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Hpa Gene expression

Bgee

ArrayExpress

Genevestigator

Hpa Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY