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Mouse E3 ubiquitin-protein ligase RAD18 (aa 1-509)

Rad18sc Swiss Prot#

Q9QXK2

Rad18sc Protein names

E3 ubiquitin-protein ligase RAD18 (EC 6.3.2.-) (Postreplication repair protein RAD18) (mRAD18Sc)

Rad18sc Gene names

Rad18 (Rad18sc)

Organism

Mouse

Rad18sc Entry name

RAD18_MOUSE

Rad18sc Codon optimized cDNA(gene) Clone

Rad18sc Cat #

RPE0374

Tag

Rad18sc contains A 6x histidine tag

Rad18sc Formulation

Liquid

Rad18sc Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Rad18sc Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Rad18sc Protein

Rad18sc Cat #

PE0374

Rad18sc Source

recombinant

Rad18sc Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Rad18sc Purity

>90%, as determined by SDS-PAGE under reducing conditions

Rad18sc Activity

N/A

Tag

Rad18sc Contains A 6x histidine tag

Rad18sc Formulation

Liquid

Rad18sc Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Rad18sc family

RAD18 family

Rad18sc Subcellular locations

Nucleus.

Rad18sc FUNCTION According to UniProtKB Swiss Prot

FUNCTION: E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.

Rad18sc Sequence

DDBJ

EMBL

GenBank

Rad18sc 3D structure

ModBase

Rad18sc interaction

STRING

Rad18sc Proteomic

PRIDE

Rad18sc Genome annotation

Ensembl

GeneID

KEGG

UCSC

Rad18sc Organism specific

CTD

MGI

Rad18sc Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Rad18sc Gene expression

Bgee

ArrayExpress

Genevestigator

Rad18sc Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY