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    Gene name, or Protein Name, or Swiss -prot Accession
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Mouse CDK-activating kinase assembly factor MAT1 (aa 1-309)
Mat1 Swiss Prot#
P51949
Mat1 Protein names
CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35)
Mat1 Gene names
Mnat1 (Mat1)
Organism
Mouse
Mat1 Entry name
MAT1_MOUSE
Mat1 Codon optimized cDNA(gene) Clone
Mat1 Cat #
RPE0314
Tag
Mat1 contains A 6x histidine tag
Mat1 Formulation
Liquid
Mat1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Mat1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Mat1 Protein
Mat1 Cat #
PE0314
Mat1 Source
recombinant
Mat1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Mat1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Mat1 Activity
N/A
Tag
Mat1 Contains A 6x histidine tag
Mat1 Formulation
Liquid
Mat1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Mat1 family
-
Mat1 Subcellular locations
Nucleus.
Mat1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Mat1 Sequence
DDBJ EMBL GenBank
Mat1 3D structure
ModBase
Mat1 interaction
STRING
Mat1 Proteomic
PRIDE
Mat1 Genome annotation
Ensembl GeneID KEGG UCSC
Mat1 Organism specific
CTD MGI
Mat1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Mat1 Gene expression
Bgee ArrayExpress Genevestigator
Mat1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY