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| Mouse CDK-activating kinase assembly factor MAT1 (aa 1-309) |
| Mat1 Swiss Prot# | | P51949 |
| Mat1 Protein names | | CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) |
| Mat1 Gene names | | Mnat1 (Mat1) |
| Organism | | Mouse |
| Mat1 Entry name | | MAT1_MOUSE |
| Mat1 Codon optimized cDNA(gene) Clone |
| Mat1 Cat # | | RPE0314 |
| Tag | | Mat1 contains A 6x histidine tag |
| Mat1 Formulation | | Liquid |
| Mat1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Mat1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Mat1 Protein |
| Mat1 Cat # | | PE0314 |
| Mat1 Source | | recombinant |
| Mat1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Mat1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Mat1 Activity | | N/A |
| Tag | | Mat1 Contains A 6x histidine tag |
| Mat1 Formulation | | Liquid |
| Mat1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Mat1 Products | | For pricing and availability Click Here >>> |
| Mat1 family | | - |
| Mat1 Subcellular locations | | Nucleus. |
| Mat1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. |
| Mat1 Sequence | | DDBJ | EMBL | GenBank |
| Mat1 3D structure | | ModBase |
| Mat1 interaction | | STRING |
| Mat1 Proteomic | | PRIDE |
| Mat1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Mat1 Organism specific | | CTD | MGI |
| Mat1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Mat1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Mat1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |