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Human Cytochrome c oxidase subunit 1 (aa 1-513)

CO1 Swiss Prot#

Q7GXY8

CO1 Protein names

Cytochrome c oxidase subunit 1 (EC 1.9.3.1)

CO1 Gene names

COX1 (CO1) (COI)

Organism

Human

CO1 Entry name

Q7GXY8_HUMAN

CO1 Codon optimized cDNA(gene) Clone

CO1 Cat #

RPE0253

Tag

CO1 contains A 6x histidine tag

CO1 Formulation

Liquid

CO1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CO1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CO1 Protein

CO1 Cat #

PE0253

CO1 Source

recombinant

CO1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CO1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CO1 Activity

N/A

Tag

CO1 Contains A 6x histidine tag

CO1 Formulation

Liquid

CO1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CO1 family

Heme-copper respiratory oxidase family

CO1 Subcellular locations

Mitochondrion inner membrane; Multi-pass membrane protein.

CO1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).

CO1 Sequence

DDBJ

EMBL

GenBank

CO1 3D structure

ModBase

CO1 interaction

STRING

CO1 Proteomic

PRIDE

CO1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CO1 Organism specific

CTD

MGI

CO1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CO1 Gene expression

Bgee

ArrayExpress

Genevestigator

CO1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY