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Human E3 ubiquitin-protein ligase RAD18 (aa 1-495)

RNF73 Swiss Prot#

Q9NS91

RNF73 Protein names

E3 ubiquitin-protein ligase RAD18 (EC 6.3.2.-) (Postreplication repair protein RAD18) (hRAD18) (hHR18) (RING finger protein 73)

RNF73 Gene names

RAD18 (RNF73)

Organism

Human

RNF73 Entry name

RAD18_HUMAN

RNF73 Codon optimized cDNA(gene) Clone

RNF73 Cat #

RPE0237

Tag

RNF73 contains A 6x histidine tag

RNF73 Formulation

Liquid

RNF73 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RNF73 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RNF73 Protein

RNF73 Cat #

PE0237

RNF73 Source

recombinant

RNF73 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RNF73 Purity

>90%, as determined by SDS-PAGE under reducing conditions

RNF73 Activity

N/A

Tag

RNF73 Contains A 6x histidine tag

RNF73 Formulation

Liquid

RNF73 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RNF73 family

RAD18 family

RNF73 Subcellular locations

Nucleus.

RNF73 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.

RNF73 Sequence

DDBJ

EMBL

GenBank

RNF73 3D structure

ModBase

RNF73 interaction

STRING

RNF73 Proteomic

PRIDE

RNF73 Genome annotation

Ensembl

GeneID

KEGG

UCSC

RNF73 Organism specific

CTD

MGI

RNF73 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RNF73 Gene expression

Bgee

ArrayExpress

Genevestigator

RNF73 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY