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Human Metalloreductase STEAP3 (aa 1-488)

TSAP6 Swiss Prot#

Q658P3

TSAP6 Protein names

Metalloreductase STEAP3 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) (Dudulin-2)

TSAP6 Gene names

STEAP3 (TSAP6)

Organism

Human

TSAP6 Entry name

STEA3_HUMAN

TSAP6 Codon optimized cDNA(gene) Clone

TSAP6 Cat #

RPE0233

Tag

TSAP6 contains A 6x histidine tag

TSAP6 Formulation

Liquid

TSAP6 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TSAP6 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TSAP6 Protein

TSAP6 Cat #

PE0233

TSAP6 Source

recombinant

TSAP6 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TSAP6 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TSAP6 Activity

N/A

Tag

TSAP6 Contains A 6x histidine tag

TSAP6 Formulation

Liquid

TSAP6 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TSAP6 family

STEAP family

TSAP6 Subcellular locations

Endosome membrane; Multi-pass membrane protein.

TSAP6 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

TSAP6 Sequence

DDBJ

EMBL

GenBank

TSAP6 3D structure

ModBase

TSAP6 interaction

STRING

TSAP6 Proteomic

PRIDE

TSAP6 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TSAP6 Organism specific

CTD

MGI

TSAP6 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TSAP6 Gene expression

Bgee

ArrayExpress

Genevestigator

TSAP6 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY