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Human Keratin type I cytoskeletal 18 (aa 2-430)

CYK18 Swiss Prot#

P05783

CYK18 Protein names

Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) (K18) (Cell proliferation-inducing gene 46 protein)

CYK18 Gene names

KRT18 (CYK18) (PIG46)

Organism

Human

CYK18 Entry name

K1C18_HUMAN

CYK18 Codon optimized cDNA(gene) Clone

CYK18 Cat #

RPE0190

Tag

CYK18 contains A 6x histidine tag

CYK18 Formulation

Liquid

CYK18 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CYK18 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CYK18 Protein

CYK18 Cat #

PE0190

CYK18 Source

recombinant

CYK18 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CYK18 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CYK18 Activity

N/A

Tag

CYK18 Contains A 6x histidine tag

CYK18 Formulation

Liquid

CYK18 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CYK18 family

Intermediate filament family

CYK18 Subcellular locations

Cytoplasm > perinuclear region.

CYK18 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

CYK18 Sequence

DDBJ

EMBL

GenBank

CYK18 3D structure

ModBase

CYK18 interaction

STRING

CYK18 Proteomic

PRIDE

CYK18 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CYK18 Organism specific

CTD

MGI

CYK18 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CYK18 Gene expression

Bgee

ArrayExpress

Genevestigator

CYK18 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY