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Human Histone-binding protein RBBP4 (aa 2-425) |
RBAP48 Swiss Prot# | | Q09028 |
RBAP48 Protein names | | Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) |
RBAP48 Gene names | | RBBP4 (RBAP48) |
Organism | | Human |
RBAP48 Entry name | | RBBP4_HUMAN |
RBAP48 Codon optimized cDNA(gene) Clone |
RBAP48 Cat # | | RPE0188 |
Tag | | RBAP48 contains A 6x histidine tag |
RBAP48 Formulation | | Liquid |
RBAP48 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
RBAP48 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
Recombinant RBAP48 Protein |
RBAP48 Cat # | | PE0188 |
RBAP48 Source | | recombinant |
RBAP48 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
RBAP48 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
RBAP48 Activity | | N/A |
Tag | | RBAP48 Contains A 6x histidine tag |
RBAP48 Formulation | | Liquid |
RBAP48 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
Place Order for Recombinant RBAP48 Products | | For pricing and availability Click Here >>> |
RBAP48 family | | WD repeat RBAP46/RBAP48/MSI1 family |
RBAP48 Subcellular locations | | Nucleus. |
RBAP48 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
RBAP48 Sequence | | DDBJ | EMBL | GenBank |
RBAP48 3D structure | | ModBase |
RBAP48 interaction | | STRING |
RBAP48 Proteomic | | PRIDE |
RBAP48 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
RBAP48 Organism specific | | CTD | MGI |
RBAP48 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| InParanoid | OrthoDB | PhylomeDB | OMA |
RBAP48 Gene expression | | Bgee | ArrayExpress | Genevestigator |
RBAP48 Family and domain | | InterPro | PROSITE | ProtoNet |
FOR in vitro RESEARCH USE ONLY |