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Human Calreticulin (aa 17-417)

CRTC Swiss Prot#

P27797

CRTC Protein names

Calreticulin (CRP55) (Calregulin) (HACBP) (ERp60) (grp60)

CRTC Gene names

CALR (CRTC)

Organism

Human

CRTC Entry name

CALR_HUMAN

CRTC Codon optimized cDNA(gene) Clone

CRTC Cat #

RPE0178

Tag

CRTC contains A 6x histidine tag

CRTC Formulation

Liquid

CRTC Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CRTC Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CRTC Protein

CRTC Cat #

PE0178

CRTC Source

recombinant

CRTC Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CRTC Purity

>90%, as determined by SDS-PAGE under reducing conditions

CRTC Activity

N/A

Tag

CRTC Contains A 6x histidine tag

CRTC Formulation

Liquid

CRTC Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CRTC family

Calreticulin family

CRTC Subcellular locations

Endoplasmic reticulum lumen. Cytoplasm > cytosol. Secreted > extracellular space > extracellular matrix. Cell surface.

CRTC FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.

CRTC Sequence

DDBJ

EMBL

GenBank

CRTC 3D structure

ModBase

CRTC interaction

STRING

CRTC Proteomic

PRIDE

CRTC Genome annotation

Ensembl

GeneID

KEGG

UCSC

CRTC Organism specific

CTD

MGI

CRTC Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CRTC Gene expression

Bgee

ArrayExpress

Genevestigator

CRTC Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY