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Human FK506-binding protein 8 (aa 1-412)

FKBP38 Swiss Prot#

Q14318

FKBP38 Protein names

FK506-binding protein 8 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (38 kDa FK506-binding protein) (hFKBP38) (FKBPR38)

FKBP38 Gene names

FKBP8 (FKBP38)

Organism

Human

FKBP38 Entry name

FKBP8_HUMAN

FKBP38 Codon optimized cDNA(gene) Clone

FKBP38 Cat #

RPE0176

Tag

FKBP38 contains A 6x histidine tag

FKBP38 Formulation

Liquid

FKBP38 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FKBP38 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FKBP38 Protein

FKBP38 Cat #

PE0176

FKBP38 Source

recombinant

FKBP38 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FKBP38 Purity

>90%, as determined by SDS-PAGE under reducing conditions

FKBP38 Activity

N/A

Tag

FKBP38 Contains A 6x histidine tag

FKBP38 Formulation

Liquid

FKBP38 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FKBP38 family

-

FKBP38 Subcellular locations

Mitochondrion membrane; Single-pass membrane protein; Cytoplasmic side.

FKBP38 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

FKBP38 Sequence

DDBJ

EMBL

GenBank

FKBP38 3D structure

ModBase

FKBP38 interaction

STRING

FKBP38 Proteomic

PRIDE

FKBP38 Genome annotation

Ensembl

GeneID

KEGG

UCSC

FKBP38 Organism specific

CTD

MGI

FKBP38 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FKBP38 Gene expression

Bgee

ArrayExpress

Genevestigator

FKBP38 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY